Catharsians are a race of mechanical aliens, similar in size and stature to Cybertronians. They come from Catharsia Station, on the edge of a star system whose civilization destroyed itself.

They derive their sentience from their "warm-wired" physiology, a term to distinguish themselves from “cold-wired” machines. Their code and circuitry was designed to be self-modifiable while in use.

Catharsians spend time on Catharsia Station in shifts, working throughout the galaxy otherwise. Despite their significant advantages in combat, Carthians very rarely work as soldiers or law enforcement. They are often technicians, craftsman, and merchants.